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QUEST FOR ADVANCED CONDITION Pain X Anti-Inflammatory |
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Pain X (therapeutic) | Biogenesis Nutraceuticals 90 veggie capsules $31.98
What is Pain-X Anti-inflammatory? DL Phenylalanine (DLPA): has putative antidepressant and analgesic (pain relieving) properties.
Pain-X Anti-inflammatory:
Boswellia: has been used in traditional Indian medicine for chronic rheumatic inflammation. Boswellic acids have been shown to inhibit 5-lipoxygenase the enzyme in leukotriene biosynthesis. It is this property along with its ability to inhibit both the classical and alternative complement pathways that accounts for its anti-inflammatory properties. Curcumin: the yellow pigment from the plant Curcuma longa, has been used traditionally to treat sprains and inflammation. Studies show that curcumin inhibits leukotriene synthesis, platelet aggregation, neutrophil inflammatory response, blocks activation of NF Kappa B and promotes fibrinolysis. Curcumin may potentiate endogenous corticosteroids, thus having indirect anti-inflammatory actions as well. Curcumin was as effective as cortisone or phenylbutazone in models of acute inflammation, but only half as effective in chronic models. However, while phenylbutazone and cortisone are associated with significant toxicity, curcumin displayed virtually no toxicity. Bromelain: was introduced as a medicinal agent in 1957, and since that time over 400 scientific papers on its therapeutic applications have appeared. Bromelain has been reported in these studies to exert a wide variety of beneficial effects, including reducing inflammation in cases of joint disease, sports injury or trauma, and preventing swelling after trauma or surgery. Bromelain selectively stimulates the production of the anti-inflammatory Prostaglandin E1 and inhibits the production of the pro-inflammatory Prostaglandin E2. Note: Bromelain may enhance the anticoagulant activity of such drugs as warfarin and aspirin. White Willow Bark: is traditionally used to treat pain. The efficacy of this botanical is due mainly to the proportion of salicin present. The salicin which is a precursor to salicylic acid works as an antipyretic, antiphlogistic and as an analgesic. Guggal: has been used traditionally for inflammation of the mouth and pharynx. Currently guggal is recommended for chronic inflammatory conditions. Bioflavonoids: have been shown to possess antioxidant, anti-inflammatory, anti-allergic, and vasoprotective actions. Hesperidin appears to inhibit phospholipase A2, lipoxygenase and cyclo-oxygenase inflammatory mediators as well as inhibit histamine release. Ginger: inhibits platelet thromboxane formation, lipoxygenase, Arachidonic acid metabolism, leukotriene and inflammatory prostaglandin production. Ginger has anti-inflammatory actions. In one small study, consisting of 10 patients, complaining of chronic muscular pain and discomfort, ginger relieved the pain and swelling in 100% of the patients. These patients were evaluated for periods ranging from 3 months to 2.5 years. Rosemary: has a traditionally been recommended for muscular rheumatism. Rosemary has antioxidant actions. Papain, Trypsin and Alpha Chymotrypsin: are proteolytic enzymes. Administration of proteolytic enzymes may speed healing of injuries. Proteolytic enzymes have allowed athletes to return to performance sooner than control groups. Chymotrypsin, and trypsin have been shown to reduce edema and inflammation. How Do I Use Pain-X? Suggested Dose: As a dietary supplement, take 1-2 capsules without food three times per day or as directed by a health care professional. Pain-X Supplement Facts:
References: Ehrenpreis S. Pharmacology of enkephalinase inhibitors: animal and human studies. Acupunct Electrother Res. 1985; 10:203-208. Walsh ND, Ramamurthy S. Schoenfeld L, Hoffman J. Analgesic effectiveness of D-phenylalanine in chronic pain patients. Arch Phys Med Rehabil. 1986; 67:436-439. Webach, MR, Murray MT. Botanical Influences on Illness: A sourcebook of clinical research. Third Line Press, Tarzana, CA, 2000. Rall B et al., Boswellic acids and protease activity (s. auch folgende Abstracts). In: PM 61 (Abstracts of 43rd Ann Congr): 105. 1995. Singh GB, Singh S, Bani S. Anti-inflammatory actions of boswellic acids. Phytomedicine 3(1):81-5, 1996. Srimal R, Dhawan B. Pharmacology of diferuloyl methane (curcumin), a non-steroidal anti-inflammatory agent. J Pharm Pharmac 25: 447-52, 1973. Taussig S, Batkin S. Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application. An update. J Ethnopharmacol 22:191-203, 1988. Taussig SJ. The mechanism of the physiological action of bromelain. Med Hypothesis 6:99-104, 1980. Vellini M et al. Possible involvement of eicosanoids in the pharmacological action of bromelain. Arzneimittelforschung 36:110-12, 1986. PDR for Herbal Medicines, Medical Economics Company, Montvale, New Jersey. 1998. Emin JA, Oliveira AB, Lapa AJ. Pharmacological evaluation of the anti-inflammatory activity of a citrus bioflavonoid, hesperidin, and the isoflavonoids duartin and claussequinone in rats and mice. J Pharm Pharmacol. 46:118-122, 1994. Srivastava KC and Mustafa T. Ginger (Zingiber officinale) in rheumatism and musculoskeletal disorders. Med Hypothesis 39:342-8, 1992. Cichoke AJ, Marty L. The use of proteolytic enzymes with soft tissue athletic injuries. Am Chiropractor October 1981, p. 32. Taraye JP, Lauressergues H. Advantages of a combination of proteolytic enzymes, flavonoids and ascorbic acid in comparison with non-steroidal inflammatory agents. Arzneim Forsch 27(1):1144-49, 1977. This information is not intended as medical advice. This information is not intended to provide you a diagnosis or a plan of care. If you are not feeling well, please consult your health care provider. If you are presently being treated by another provider, do not disregard that provider's treatment plan because of anything that you read on this website. If you have any questions, please call or email us. Your well-being is our primary concern. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. 
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