What is Alpha R-Lipoic Acid (bioactive ARLA)? Alpha R-Lipoic Acid is the natural, bio-identical form of ALA. Alpha R-Lipoic Acid contains no synthetic Alpha S-Lipoic Acid (ASLA). Regular Alpha Lipoic Acid contains 50% synthetic ASLA. Only Alpha R-Lipoic Acid has strong biological antioxidant enhancing properities and is important for cellular health.

Alpha R-Lipoic Acid (bioactive ARLA): Alpha Lipoic acid is a naturally occurring chemical produced by every cell in the body. Alpha Lipoic Acid has been called the "metabolic antioxidant" by Dr. Lester Packer, considered one of the world's leading experts in antioxidant research. Even though Lipoic acid is made naturally within the body there is good evidence that our bodies can lose the ability to synthesize enough Lipoic acid when we need it most.

Also, the body produces small amounts of R-Lipoic acid necessary for metabolism, but this may not meet the needs of the body for free radical quenching. Supplementation may be beneficial and can produce profound therapeutic benefits. R-Lipoic acid is the only form of lipoic acid that your body synthesizes and can safely metabolize R-Lipoic acid is the only form of lipoic acid that is proven to significantly reduce inflammation, an underlying cause of aging.

Alpha R-Lipoic Acid (bioactive ALA):

Biologically active form of alpha lipoic acid
Acts as a metabolic antioxidant
Critical role in regulating normal metabolism and energy production
Powerful scavenger of dangerous free radicals
Neuroprotective and regenerative
Immunoprotective and supportive
Supports reduction of inflammation
Enhances glucose transport

Alpha R-Lipoic Acid (bioactive ALA): Chronic systemic inflammation is a prerequisite for ALL the chronic degenerative diseases of aging. Alpha R-Lipoic Acid has a positive effect in quenching inflammation!

Alpha RS-Lipoic acid (Alpha Lipoic Acid or ALA) has been used in Europe in doses between 500 to 1000mg per day, producing profound benefits in patients with glucose regulation disturbances, nerve conditions and insulin resistance. Scientists are now applying the active form of ALA, Alpha R-Lipoic acid to even more challenging cases!

Consistently consuming large amounts of R-Lipoic Acid may help prevent viral activation, even in serious viral conditions. Severe neurodegenerative diseases are showing benefit from the use of R-Lipoic Acid.

How does R-Lipoic Acid differ from Alpha Lipoic Acid? Molecules in living systems generally exist in only one form. When the same molecules are synthesized in the laboratory they consist of equal amounts of both forms. Examples of this would include: dl alpha tocopherol (synthetic Vitamin E) and d alpha tocopherol (natural Vitamin E). The synthetic 'unnatural' form of ALA is Alpha RS-Lipoic Acid or more commonly called alpha lipoic acid and the natural "fully active' form is alpha R-Lipoic acid. The 'R' form is the proper structural fit for membrane receptors and enzymes and therefore is metabolized more efficiently and with much greater potency.

Taking more synthetic ALA has not been shown to give the same benefit as R-Lipoic Acid. It is best to avoid Alpha RS-Lipoic Acid! Apparently the S-Lipoic Acid form actually interferes with the proper metabolism of the bioactive R-form. In one animal study with mice ALA at high doses shortened their mean lifespan, but even low doses of the R- form increased their total lifespan.

Alpha R-Lipoic acid has been reported to be 10 times more powerful than standard Alpha RS-Lipoic Acid!

How Do I Use Alpha R-Lipoic Acid? Suggested Dose: As a dietary supplement, take 1-2 capsules twice daily or as directed by your health care practitioner. Alpha R-Lipoic Acis is also used as part of the Environmental Cocktail Detox.

Alpha R-Lipoic Acid Supplement Facts:

alpha r-lipoic acid by biogeneis nutraceuticals

References:

Moini H., Tirosh O. R-Alpha Lipoic Acid Action on Cell Redox Status, the Insulin Receptor, and Glucose Uptake in 3T3-L1 Adipocytes. Achives of Biochem & Phys 397, No2 384-391, 2002.

Liu J, Killilea DW, et. al. Age-associated mitochondrial oxidative decay: Improvement of carnitine acetyltransferase substrate binding affinity and activity in brain by feeding old rats acetyl-L-carnitine and/or R-alpha -lipoic acid. Proc nat Acad Sci 99, 1876-1881, 2002.

Packer L, Tritschler HJ. Neuroprotection by the Metabolic Antioxidant Alpha Lipoic Acid. Free Rad Biol Med 22, Nos ½, 359-378, 1997.

Hermann R, Niebch G. Enantioselective pharmacokinetics and bioavailability of different racemic alpha lipoic acid formulations in healthy volunteers. Eur J Pharm Sci 4: 167-174, 1996.

Liu J, Head E, et al. Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: Partial reversal by feeding acetyl-l-carnitine and/or R-alpha lipoic acid. Proc Natl Acad Sci USA 99, 2356-2361, 2002.

Liu J, Atamna H, et al. Delaying Brain Mitochondrial Decay and Aging with Mitochondrial Antioxidants and metabolites. Ann NY Acad Sci 959:133-166, 2002.

Hager K, Marahrens A et al. Alpha lipoic acid as a new treatment option for Alzheimer type dementia. Arch Geron Geriatr 32(3): 275-282, 2001.

This information is not intended as medical advice. This information is not intended to provide you a diagnosis or a plan of care. If you are not feeling well, please consult your health care provider. If you are presently being treated by another provider, do not disregard that provider's treatment plan because of anything that you read on this website. If you have any questions, please call or email us. Your well-being is our primary concern.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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