The Sex Hormones: Testosterone and Estrogen by
Dr. Rick Cohen
Testosterone: The Master Male Hormone - Suppose
someone told you there was a magical substance that could increase
your sex drive, strengthen your bones and muscles, decrease your
body fat, improve your thinking ability, boost your energy levels,
and guard against the onset of depression and heart disease as you
age. You might be skeptical. Or you might be tempted to go out and
buy a whole truckload of it. In reality, these effects are all a
real possibility. And they are made possible by a substance that
is naturally produced by your own body—the male sex hormone
testosterone.
What is Testosterone? It’s a powerful anabolic
hormone that stimulates and controls the development of muscle,
bone, skin, sex organs, and most other masculine, physical features.
Recently, scientists have discovered that testosterone also aids
mental function, enhancing both visual and perceptual skills. Male,
testosterone is produced in the testes by a group of cells known
as the Leydig cells. These cells begin secreting high doses of testosterone
during puberty to trigger increased lean muscle mass, sex organ
development, bone formation and higher energy levels. Testosterone
levels peak during a man's early to mid twenties.
As a man ages, the amount of testosterone produced by the Leydig
cells decreases. By the age of sixty, the average man will have
lost nearly 50% of his testosterone supply. In addition, other factors
(such as stress, lack of sleep, physical inactivity, the use of
prescription medication and drinking) can cause testosterone levels
to drastically decline. Although there is a growing awareness of
the vital role testosterone plays in a man’s overall health,
the vast majority of men still don't recognize the key symptoms
of testosterone deficiency. These symptoms include depression, fatigue,
low sex drive, irritability, loss of facial/body hair, thinning
and/or wrinkling of skin, weight gain, and the weakening of both
bone and muscle tissue. Eventually, imbalances of testosterone can
set the stage for the development of more serious disease. Low testosterone
levels can also disrupt the body's blood sugar metabolism, leading
to obesity and diabetes. Chronic deficiencies may also promote the
early onset of osteoporosis and heart disease.
Can low testosterone affect your sex life? Yes!
Since ancient times men have searched for ways to increase their
virility. Today, there are many popular medications that improve
the physical factors (such as circulation) needed to sustain an
erection. Yet many men do not realize that none of these medicines
are long-term solutions, as they simply cannot play substitute for
testosterone. Testosterone is, in a sense, your body's own natural
aphrodisiac.
Estrogen: Not for women only - Just as many women
are not aware that their bodies produce and rely upon small amounts
of testosterone for healthy physical and mental function, most men
don’t know that their bodies produce and depend on small amounts
of estrogen. Produced in the fat cells and liver of a man’s
body, male estrogen is a natural by-product of testosterone metabolism.
There are three main forms of estrogen—estradiol, estrone,
and estriol—with estradiol being the most biologically-active.
Obesity, pesticides, nutritional deficiencies, prescription medications
and excessive alcohol intake can all promote the onset of high estrogen
levels, which can directly inhibit the production and activity of
testosterone. This condition commonly leads to a high body-fat percentage
and often to diabetes, cardiovascular disease and prostate enlargement.
Since high levels of estrogen are typically linked to low bio-available
testosterone levels, those experiencing symptoms or low testosterone
levels should also assess their levels of estradiol.
The Stress Hormones: Cortisol and DHEA - Your
body responds to stress by producing increased amounts of cortisol
and DHEA, hormones that minimize the negative, physiologic effects
of stress. Because the body was designed to manage acute, life-threatening
stress, it is not well equipped to handle the more constant on-going
stress with life in the modern world.
Because of this, the body can easily become overwhelmed and incapable
of producing adequate supplies of cortisol and DHEA. The end result?
Stress hormone imbalance, which can lean to fatigue, insomnia and
loss of libido. Chronic stress and stress hormone imbalance can
also cause low testosterone, mood changes, depression, anxiety,
poor immune response, cancer, cardiovascular disease, pre-mature
aging and auto-immune disorders (such as lupus, MS, rheumatoid arthritis,
fibromyalgia and chronic fatigue syndrome).
Cortisol: Important for protecting the body in
times of stress - Cortisol is an important steroid hormone produced
in the adrenal glands. Without proper cortisol levels, meeting life’s
daily challenges would be difficult. While short-term elevations
of cortisol represent a normal adaptive response to life-threatening
situations, injury and/or illness, prolonged cortisol elevations
are extremely unhealthy and harmful. Chronically-high cortisol levels
have been linked to depression, osteoporosis, obesity, heart disease,
cancer and diabetes.
DHEA: An important building block - DHEA is the
most abundant steroid hormone found in the human body, and it has
long been identified as an important building block (precursor)
for testosterone. Over the past 10 years, however, research has
also confirmed that DHEA performs many other important functions.
The most critical of these? Aiding the body in adapting to and coping
with stress. Low levels of DHEA have been associated with poor immune
function, depression, cardiovascular disease, Alzheimers disease,
hypothyroidism, and diabetes.
Hormonal Balancing: Tying it all together - Whether
your goals are to maximize your athletic performance or simply optimize
your overall level of health, an adequate balance of both the anabolic
(testosterone and DHEA) and catabolic (cortisol and estrogen) hormones
is key. The terms "anabolic" and "catabolic"
refer to the specific effect that these hormones have on the growth,
maintenance and repair of cells inside your body. Anabolic hormone
levels reach their peak during a man’s twenties and decrease
with age. These powerful hormones are essential for healthy muscle
growth, tissue repair, immune response and metabolism. (Click here
for further information in regards to dietary supplements specifically
for pre and post recovery workouts) Catabolic hormones have just
the opposite effect. They promote muscle and tissue breakdown, decreased
immunity and reduced metabolism. Catabolic hormones increase with
age, stress, and illness. Optimal health is a state characterized
by a high ratio of anabolic to catabolic hormones. Only through
comprehensive hormonal testing of testosterone, DHEA, estrogen and
cortisol can this important ratio be assessed. Testosterone and
DHEA levels should be in the high normal range. Levels of estrogen
and cortisol should be in the low normal range. Comprehensive hormonal
testing can be a useful tool in providing insights into the cause
of low testosterone. High estrogen may be at the root of the problem
inhibiting testosterone production. And stress may be the culprit
when low DHEA and/or abnormal cortisol levels are observed.
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